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The authors report that this new strain has caused only mild illness in cattle. However, genotype D1.1 was detected in a severe human case in British Columbia and a reportedly fatal human case in Louisiana. The study identified the PB2 D701N mutation in all sequenced cattle-derived D1.1 viruses, a change that has frequently emerged following mammalian spillover in previous H5N1 outbreaks.
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Author: Nicolas Hulscher, MPH
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