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Health and Human Services (HHS) Secretary Robert F. Kennedy Jr. made headlines earlier this week by saying the National Institutes of Health (NIH) is developing a “universal vaccine.”
NIH Developing A “Universal Vaccine” – HHS Secretary Robert F. Kennedy Jr. Says
“Right now, we’re developing a universal vaccine at NIH, which is a vaccine that addresses the entire phylum of viruses,” RFK Jr. said.
“It’s a vaccine that mimics natural immunity, and it is effective against any kind of mutations,” he continued.
“We believe it’s going to be effective against not only coronaviruses but also flu,” he added.
Check it out:
RFK Jr says the NIH is developing a “universal vaccine” for COVID and Flu which mimics natural immunity pic.twitter.com/Te66wv0VIX
— Chief Nerd (@TheChiefNerd) August 8, 2025
“The U.S. Department of Health and Human Services (HHS) and the National Institutes for Health (NIH) today announced the development of the next-generation, universal vaccine platform, Generation Gold Standard, using a beta-propiolactone (BPL)-inactivated, whole-virus platform,” the NIH stated in May.
“This initiative represents a decisive shift toward transparency, effectiveness, and comprehensive preparedness, funding the NIH’s in-house development of universal influenza and coronavirus vaccines, including candidates BPL-1357 and BPL-24910. These vaccines aim to provide broad-spectrum protection against multiple strains of pandemic-prone viruses such as H5N1 avian influenza and coronaviruses including SARS-CoV-2, SARS-CoV-1, and MERS-CoV,” it continued.
“Our commitment is clear: every innovation in vaccine development must be grounded in gold standard science and transparency, and subjected to the highest standards of safety and efficacy testing,” RFK Jr. said.
More from the NIH:
The program realigns BARDA’s operations with its statutory mission under the Public Health Service Act—to prepare for all influenza viral threats, not just those currently circulating.
“Generation Gold Standard is a paradigm shift,” said NIH Director Dr. Jay Bhattacharya. “It extends vaccine protection beyond strain-specific limits and prepares for flu viral threats – not just today’s, but tomorrow’s as well – using traditional vaccine technology brought into the 21st century.”
Generation Gold Standard, developed exclusively by NIH’s National Institute of Allergy and Infectious Diseases (NIAID):
- Recalibrates America’s pandemic preparedness. Unlike traditional vaccines that target specific strains, BPL-inactivated whole-virus vaccines preserve the virus’s structural integrity while eliminating infectivity. This approach induces robust B and T cell immune responses and offers long-lasting protection across diverse viral families. Moreover, the intranasal formulation of BPL-1357 is currently in Phase Ib and II/III trials and is designed to block virus transmission—an innovation absent from current flu and COVID-19 vaccines.
- Embodies efficient, transparent, and government-led research. The BPL platform is fully government-owned and NIH-developed. This approach ensures radical transparency, public accountability, and freedom from commercial conflicts of interest.
- Marks the future of vaccine development. In addition to influenza and coronavirus, the BPL platform is adaptable for future use against respiratory syncytial virus (RSV), metapneumovirus, and parainfluenza. It also offers the unprecedented capability to protect against avian influenza without inducing antigenic drift—a major step forward in proactive pandemic prevention.
Clinical trials for universal influenza vaccines are scheduled to begin in 2026, with Food and Drug Administration (FDA) approval targeted for 2029. The intranasal BPL-1357 flu vaccine, currently in advanced trials, is also on track for FDA review by 2029.
“You know that new ‘universal vaccine’ that RFK Jr. was just touting? It’s called BPL-1357 – a beta-propiolactone inactivated, whole-virus ‘universal influenza’ vaccine developed in-house at NIH’s NIAID. You’ll never guess who is funding its production? Bill Gates,” writer and Zero Hedge contributor Josh Walkos said.
You know that new “universal vaccine” that RFK Jr. was just touting?
It’s called BPL-1357 – a beta-propiolactone inactivated, whole-virus “universal influenza” vaccine developed in-house at NIH’s NIAID.
You’ll never guess who is funding its production?
Bill Gates. pic.twitter.com/mA30UovWa6
— Champagne Joshi (@JoshWalkos) August 9, 2025
* Screenshots from Josh Walkos X Post *
“Here is a screenshot shot of the post that was deleted after backlash along with the announcement for the universal vaccine platform that uses the BLP platform,” Walkos added.
Here is a screenshot shot of the post that was deleted after backlash along with the announcement for the universal vaccine platform that uses the BLP platform.https://t.co/OmxgOCJRbs… pic.twitter.com/BVed9a3ADr
— Champagne Joshi (@JoshWalkos) August 9, 2025
Read the full 68-page NIH document on the BPL-1357 Phase I trials (Page 15 cites the funding).
“A Phase 1 clinical trial of a novel influenza vaccine has begun inoculating healthy adult volunteers at the National Institutes of Health Clinical Center in Bethesda, Maryland. The placebo-controlled trial will test the safety of a candidate vaccine, BPL-1357, and its ability to prompt immune responses. The vaccine candidate was developed by researchers at the National Institute of Allergy and Infectious Diseases (NIAID). The single-site trial can enroll up to 100 people aged 18 to 55 years and is led by NIAID investigator Matthew J. Memoli, M.D,” the NIH wrote in 2022.
“Influenza vaccines that can provide long-lasting protection against a wide range of seasonal influenza viruses as well as those with pandemic potential would be invaluable public health tools,” former NIAID Director Anthony Fauci said.
“The scientific community is making progress on this pressing global health priority. The BPL-1357 candidate influenza vaccine being tested in this clinical trial performed very well in pre-clinical studies and we look forward to learning how it performs in people,” he continued.
More from the NIH in 2022:
BPL-1357 is a whole-virus vaccine made up of four strains of non-infectious, chemically inactivated, low-pathogenicity avian flu virus. A study in animals, led by NIAID investigator Jeffery K. Taubenberger, M.D., Ph.D., and posted online as a pre-print, found that all mice receiving two doses of BPL-1357 vaccine delivered either intramuscularly or intranasally survived later exposure to lethal doses of each of six different influenza virus strains, including subtypes that were not included in the vaccine. Similar results were obtained in challenge experiments with BPL-1357-vaccinated ferrets.
In the Phase 1 trial, volunteers will be randomized in a 1:1:1 ratio into three groups and will receive two doses of placebo or vaccine spaced 28 days apart. Group A participants receive BPL-1357 intramuscularly along with intranasal saline placebo; Group B will receive doses of the candidate vaccine intranasally along with intramuscular placebo; volunteers in Group C receive intramuscularly and intranasally delivered placebo at both visits to the clinic. Neither the study clinicians nor the volunteers know the group assignments. Volunteers must not have received any type of flu vaccination in the eight weeks prior to enrollment and must agree to forego seasonal flu vaccination for approximately two months after the second vaccine (or placebo) dose.
The study duration for each participant is approximately seven months. In addition to the two clinic visits to receive vaccine (or placebo), volunteers will be asked to return to the clinic seven times to provide blood and nasal mucosal samples that will be used by the investigators to detect and characterize immune responses.
“With the BPL-1357 vaccine, especially when given intranasally, we are attempting to induce a comprehensive immune response that closely mimics immunity gained following a natural influenza infection,” said Dr. Memoli. “This is very different than nearly all other vaccines for influenza or other respiratory viruses, which focus on inducing immunity to a single viral antigen and often do not induce mucosal immunity.”
“Our study will examine the safety of BPL-1357 and also will allow us to assess the importance of mucosal immunity against flu and whether a strategy of inducing both the cellular and antibody arms of the immune system can provide broader protection against the ever-changing influenza virus,” he added.