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coronavirus

Covid-19:

Trump medical adviser says Remdesivir has “positive” effect

Covid-19 patients treated with Remdesivir recovered 31 percent faster than others who received a placebo, according to a clinical study released on Wednesday that the White House chief medical adviser estimated as a “clear” effect of the drug on the disease treatment.

“The data shows that Remdesivir has a clear, significant and positive effect in reducing the recovery time” of coronavirus patients, said Dr. Anthony Fauci, an epidemiologist and adviser to President Donald Trump, on Wednesday. This proves “that a drug can block this virus,” continued Fauci, who oversaw the investigation.

Fauci compared the finding with the development of the first anti-HIV antivirals in the late 1980s.

Compared to patients receiving a placebo, those treated with Remdesivir, from the Gilead laboratory, healed in an average of 11 days instead of 15, according to a press release from the National Institutes of Health.

Regarding the effects on mortality, the results are not significant, which is to say that the difference between the two groups evaluated could be a matter of probability.

However, the Remdesivir-treated group suffered an 8 percent mortality, versus 11 percent in the placebo group, “suggesting” that the drug increases the chance of survival.

This is the first time that a drug has been shown to work against covid-19, which has claimed more than 200,000 lives worldwide and halted the global economy.

The study, which began on February 21, involved 1,063 patients, from 47 sites in the United States and another 21 sites in Europe and Asia.

His first patient was a repatriated American after being quarantined aboard the Diamond Princess cruise ship, and who received treatment at the University of Nebraska Medical Center.

Peter Horby, an epidemiologist at Oxford University who was not involved in the study, said the full results remain to be known.

“If this is confirmed it could be a fantastic result and great news for the fight against covid-19,” Horby said.

On the other hand, Scott Gottliebb, a former commissioner of the US FDA, the federal drug agency, wrote on Twitter that the data is enough to justify being considered an “authorization for emergency use.”

Such a decision would allow doctors to prescribe Remdesivir outside of the context of clinical trials.

Remdesivir, which had been unsuccessfully tested against Ebola, belongs to a class of drugs that act directly on the virus, instead of controlling the abnormal and often deadly autoimmune response it generates.

The drug manages to be absorbed by the virus genome, and thus prevents the pathogen from replicating further.

In his statements to the press, Fauci said that the success of this test could pave the way for more effective drugs that apply a similar principle.

Different and contradictory news about this intravenous antiviral had been known in recent weeks.

A summary of results published on the World Health Organization (WHO) website last week showed that there were no positive results in a smaller trial conducted in China.

British medical journal The Lancet published the formal document describing that test on Wednesday.

In the study of 237 patients in Wuhan, China, physicians found no positive effects after administration of the drug compared to a control group of adults, except for those patients who required ventilators.

But the Chinese test had to be stopped early because it was unable to recruit enough people to reach its initial objective, and because of its small size many experts considered that it did not allow reliable conclusions to be drawn.

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Covid-19: Trump medical adviser says Remdesivir has "positive" effect

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